The San Francisco 49ers joined the NFL in 1950 and have grown into one of the league’s marquee franchises. Below is the 49ers’ all-time regular-season record against every current NFL team, plus links to full head-to-head breakdowns for their NFC West rivals.
49ers All-Time Record vs Every NFL Team
| Opponent | All-Time (W-L-T) | Win % |
|---|---|---|
| Arizona Cardinals | 38-31-0 | .551 |
| Atlanta Falcons | 48-32-1 | .599 |
| Baltimore Ravens | 2-5-0 | .286 |
| Buffalo Bills | 6-8-0 | .429 |
| Carolina Panthers | 10-13-0 | .435 |
| Chicago Bears | 34-33-1 | .507 |
| Cincinnati Bengals | 11-5-0 | .688 |
| Cleveland Browns | 11-19-0 | .367 |
| Dallas Cowboys | 17-14-1 | .547 |
| Denver Broncos | 7-8-0 | .467 |
| Detroit Lions | 38-28-1 | .575 |
| Green Bay Packers | 28-35-1 | .445 |
| Houston Texans | 4-2-0 | .667 |
| Indianapolis Colts | 19-27-0 | .413 |
| Jacksonville Jaguars | 5-3-0 | .625 |
| Kansas City Chiefs | 7-8-0 | .467 |
| Las Vegas Raiders | 8-7-0 | .533 |
| Los Angeles Chargers | 7-8-0 | .467 |
| Los Angeles Rams | 78-71-3 | .523 |
| Miami Dolphins | 6-9-0 | .400 |
| Minnesota Vikings | 20-24-1 | .456 |
| New England Patriots | 10-5-0 | .667 |
| New Orleans Saints | 50-27-2 | .646 |
| New York Giants | 19-17-0 | .528 |
| New York Jets | 12-3-0 | .800 |
| Philadelphia Eagles | 20-14-1 | .586 |
| Pittsburgh Steelers | 13-10-0 | .565 |
| Seattle Seahawks | 23-31-0 | .426 |
| Tampa Bay Buccaneers | 21-7-0 | .750 |
| Tennessee Titans | 10-6-0 | .625 |
| Washington Commanders | 20-11-1 | .641 |
Head-to-Head Breakdown Pages
FAQ
Who have the 49ers played the most all-time?
The San Francisco 49ers have faced the Los Angeles Rams more than any other current NFL franchise (152 regular-season meetings).
What is the 49ers’ best all-time record against a longtime opponent?
Among teams they have played at least 10 times, the San Francisco 49ers have their best winning percentage against the New York Jets.
Are these regular-season or all-time records including playoffs?
The table shows regular-season records versus each current franchise. Playoff meetings are covered on the individual head-to-head pages linked above.
More From Sports Brackets
- Arizona Cardinals all-time records
- Los Angeles Rams all-time records
- Seattle Seahawks all-time records
