Last updated: October 27, 2026. The 2026 NFL Week 12 pick’em is here with early betting lines: point spread, over/under total, and moneyline for all 16 games. This is Thanksgiving week, so the slate is stretched across five days, from a Wednesday night opener through a Monday night finale, and there are no byes with all 32 teams in action. These are look-ahead lines posted well before kickoff; they will firm up as Week 12 gets closer and will move on injuries and betting action, so treat them as a planning guide and confirm the current number before you wager.
2026 NFL Week 12 Pick’em: Quick Facts
- Games: 16 (no byes this week).
- Wednesday night: Green Bay Packers at Los Angeles Rams (Nov 25, on Netflix).
- Thanksgiving (Thu Nov 26): Bears at Lions, Eagles at Cowboys, Chiefs at Bills.
- Black Friday: Denver Broncos at Pittsburgh Steelers (Nov 27, on Prime Video).
- Sunday night: New England Patriots at Los Angeles Chargers.
- Monday night: Carolina Panthers at Tampa Bay Buccaneers (Nov 30).
- Biggest spread: Cincinnati laying 6.5 on New Orleans tops an unusually tight board.
2026 NFL Week 12 Odds: Spreads, Totals and Moneylines
| DATE | MATCHUP (AWAY AT HOME) | SPREAD | O/U | ML (AWAY/HOME) |
|---|---|---|---|---|
| Wed Nov 25 | Green Bay Packers at Los Angeles Rams | Rams -4.5 | 48.5 | +185 / -225 |
| Thu Nov 26 | Chicago Bears at Detroit Lions | Lions -2.5 | 52.5 | +120 / -140 |
| Thu Nov 26 | Philadelphia Eagles at Dallas Cowboys | Cowboys -1.5 | 49.5 | +100 / -120 |
| Thu Nov 26 | Kansas City Chiefs at Buffalo Bills | Bills -2.5 | 50.5 | +125 / -150 |
| Fri Nov 27 | Denver Broncos at Pittsburgh Steelers | Broncos -1.5 | 39.5 | -125 / +105 |
| Sun Nov 29 | Atlanta Falcons at Minnesota Vikings | Vikings -4.5 | 43.5 | +185 / -225 |
| Sun Nov 29 | Baltimore Ravens at Houston Texans | Texans -1.5 | 45.5 | +105 / -125 |
| Sun Nov 29 | Las Vegas Raiders at Cleveland Browns | Browns -1.5 | 39.5 | +105 / -125 |
| Sun Nov 29 | New Orleans Saints at Cincinnati Bengals | Bengals -6.5 | 48.5 | +240 / -300 |
| Sun Nov 29 | New York Giants at Indianapolis Colts | Colts -2.5 | 47.5 | +115 / -135 |
| Sun Nov 29 | New York Jets at Miami Dolphins | Dolphins -1.5 | 40.5 | +105 / -125 |
| Sun Nov 29 | Tennessee Titans at Jacksonville Jaguars | Jaguars -5.5 | 45.5 | +200 / -245 |
| Sun Nov 29 | Seattle Seahawks at San Francisco 49ers | Seahawks -1.5 | 46.5 | -110 / -110 |
| Sun Nov 29 | Washington Commanders at Arizona Cardinals | Commanders -4.5 | 47.5 | -220 / +180 |
| Sun Nov 29 | New England Patriots at Los Angeles Chargers | Chargers -1.5 | 45.5 | +105 / -125 |
| Mon Nov 30 | Carolina Panthers at Tampa Bay Buccaneers | Buccaneers -3.5 | 44.5 | +165 / -200 |
Spreads, totals and moneylines are an aggregate of major sportsbooks and reflect the current look-ahead number. The home team is listed second. Lines lock once each game kicks off.
What the Week 12 Lines Are Telling Us
Week 12 is a get-together week, and the board reflects it: there is not a single double-digit spread, and only Cincinnati (-6.5 over New Orleans) and Jacksonville (-5.5 over Tennessee) are favored by more than a field goal and a half. The Thanksgiving triple-header is tight across the board, with Detroit, Dallas and Buffalo all laying a field goal or less at home, so the holiday games are live for upset-minded pickers. The fattest totals sit on the two early showcases, Bears at Lions (52.5) and Chiefs at Bills (50.5), pointing to projected shootouts, while Denver at Pittsburgh on Black Friday carries the lowest number on the slate at 39.5. With no byes to work around, every team is available, so the tight lines and the short turnaround between games are what should drive your picks.
How to Run a Week 12 Pick’em Pool
Print the sheet above, hand a copy to everyone in your group, and have each player circle the team they think covers the spread in every game. Tally one point per correct pick and use the Monday night total (Panthers at Buccaneers) as your tiebreaker: closest to the combined final score without going over wins. For a simpler office pool, ignore the spread and just pick straight-up winners. Thanksgiving week is a scheduling maze, so note that the first game kicks Wednesday night and set your lock time before that Packers-Rams opener so nobody is left out.
More 2026 NFL Resources
- 2026 NFL Weekly Schedule Hub: All Pick’em Sheets, TV Guide and PDF Grids
- 2026 NFL Week 11 Pick’em with Odds
- 2026 NFL Week 2 Pick’em with Odds
- 2026 NFL Week 1 Pick’em with Odds
- 2026 NFL Standings
2026 NFL Week 12 Pick’em: FAQ
What are the Week 12 odds based on?
These are early look-ahead Week 12 lines, posted October 27, 2026, from an aggregate of major sportsbooks. Because they are published weeks out, they move more than a game-week number, so confirm the current line before wagering.
What does the spread mean?
The spread is the margin the favorite must win by to cover. A pick on the underdog covers if that team loses by less than the number, or wins outright.
Are there any byes in Week 12?
No. Week 12 is Thanksgiving week and all 32 teams play, so every team is available for your pool sheet.
Is the Week 12 pick’em sheet free?
Yes. The printable Week 12 pick’em sheet with odds is free to download, print, and share with your pool.
Odds are provided for informational and entertainment purposes and reflect an aggregate of major sportsbooks. Must be 21 or older. If you or someone you know has a gambling problem, call 1-800-GAMBLER.
