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2026 NFL Week 10 Predictions

The 2026 NFL season rolls into Week 10 with a 14-game slate that opens in Munich, runs through a loaded Sunday, and closes with a division-tinted Monday nighter in Baltimore. Below you will find our pick for every game, straight up, with the current spread and over/under pulled from our Week 10 pick’em with odds page so the numbers line up. We flag two upset picks, break down the best bets and leans, and you can grab a free printable pick sheet for your pool. Lines move, so treat these as current as of publish.

Quick Facts

  • Week: NFL Week 10, 2026
  • Games: 14 (Thursday Nov 12 through Monday Nov 16)
  • International game: Patriots at Lions in Munich, 9:30 a.m. ET on FOX
  • Sunday Night Football: Steelers at Bengals
  • Monday Night Football: Chargers at Ravens
  • On a bye: Bears, Broncos, Eagles, Buccaneers
  • Upset picks: Vikings (+4.5) at Green Bay, Chargers (+3.5) at Baltimore
2026 NFL Week 10 predictions featured graphic

Week 10 Predictions: Every Game

Our pick is the straight-up winner. Spreads and totals are from the SportsBrackets Week 10 pick’em page and reflect the market at publish. The two rows marked Upset are games where we are taking the underdog outright.

Matchup (Away at Home)SpreadO/UOur pick
Washington at N.Y. GiantsGiants -1.547.5Giants
New England at Detroit (Munich)Lions -1.548.5Lions
Buffalo at N.Y. JetsBills -7.546.5Bills
Carolina at New OrleansSaints -1.543.5Saints
Houston at ClevelandTexans -4.538.5Texans
Jacksonville at TennesseeJaguars -2.545.5Jaguars
Kansas City at AtlantaChiefs -4.545.5Chiefs
Miami at IndianapolisColts -6.547.5Colts
Minnesota at Green BayPackers -4.545.5Vikings (Upset)
L.A. Rams at ArizonaRams -10.547.5Rams
Seattle at Las VegasSeahawks -7.543.5Seahawks
San Francisco at DallasCowboys -1.552.5Cowboys
Pittsburgh at CincinnatiBengals -3.547.5Bengals
L.A. Chargers at BaltimoreRavens -3.547.5Chargers (Upset)

Upset Watch

Vikings (+4.5) at Packers. Division road games in November tend to tighten up, and Minnesota has the kind of pass rush that can turn a cold Lambeau afternoon into a one-score slog. Green Bay is the better team on paper, but a field goal and a half feels generous for a rivalry game. We will take the points and the outright shot.

Chargers (+3.5) at Ravens (Monday night). Baltimore is favored at home in prime time, but the Chargers travel well and this line says the market still is not fully convinced either way. In a spot where both teams can move the ball, a late stop and a short field is all Los Angeles needs to steal it.

One more to keep honest: Panthers (+1.5) at Saints is essentially a coin flip, and Carolina has quietly been tougher to beat on the road than the record suggests. We landed on New Orleans, but do not be shocked if that one flips.

Best Bets and Leans

These are opinions, not locks. Think of them as the games we feel best about after lining up our picks with the spreads.

  • Texans -4.5 at Cleveland: our firmest favorite lean. Houston’s defense travels, and a 38.5 total says points will be hard to find, which favors the more complete team.
  • Cardinals +10.5 vs. Rams: double-digit home dogs in the division are worth a long look. We still picked the Rams to win, but Arizona covering would not surprise us.
  • 49ers at Cowboys Over 52.5: the highest total on the board, two offenses that can trade blows, and a dome environment. If you like a total this week, this is the one.
  • Chargers +3.5 (Monday): our upset pick doubles as a spread lean. Getting a field goal plus the hook in a near coin-flip game is value.

For entertainment only. Odds move and nothing here is a guarantee. If you bet, set a budget, treat it as the cost of fun, and play responsibly. Help is available at 1-800-GAMBLER.

Storylines to Watch

Football in Munich. The Lions host the Patriots at Allianz Arena in the early 9:30 a.m. ET window on FOX. Detroit is the designated home team, so the crowd should skew in its favor, and a short-week international trip is the kind of wrinkle that can flatten a favorite.

AFC North on Sunday night. Steelers at Bengals is the SNF headliner, a division game with real standings weight. Cincinnati is a field goal favorite at home, but these two rarely play a clean one.

49ers and Cowboys under the lights of a 52.5 total. The marquee late window game carries the highest over/under on the slate. Dallas is a short home favorite, and the shootout potential is why this is our favorite total of the week.

Four teams on a bye. Chicago, Denver, Philadelphia, and Tampa Bay are off, so fantasy managers and pool players alike need to plan around missing starters.

Printable Week 10 Pick Sheet

Running an office pool or picking with friends? Grab the free printable sheet below. It lists every Week 10 game with the spread and over/under, plus blank columns for your pick and the final score, and a Monday-night tiebreaker line.

More from Sports Brackets

Frequently Asked Questions

What are the best Week 10 upset picks?

Our two flagged upsets are the Vikings (+4.5) at Green Bay and the Chargers (+3.5) at Baltimore on Monday night. Both are underdogs we like to win outright, not just cover.

Where do the spreads come from?

They are pulled from our Week 10 pick’em with odds page, which tracks the market consensus. Lines move through the week, so the numbers here reflect publish time.

When is the Week 10 Monday night game?

Chargers at Ravens kicks off Monday, November 16 at 8:15 p.m. ET on ESPN. It is our second upset pick of the week.

Is the printable pick sheet free?

Yes. The Week 10 pick sheet is a free PDF with every game, the spread and over/under, and blank columns for your picks and scores. It opens in a new tab so you can print it.

author avatar
Will Lewis Editor, Author
Will Lewis has covered sports for over 18 years, specializing in bracketology, tournament predictions, and in-depth analysis across college hoops, NFL, NBA, NHL, MLB, and more. March Madness is his favorite season, fueling his quest for perfect brackets before diving into pro playoffs. A lifelong Kentucky Wildcats fan, Bengals supporter since the Joe Montana era, and now a Padres devotee, Will delivers reliable, fan-first insights at Sports Brackets. Connect on X or comment. He loves talking brackets and more.