Week 3 is here, and the board has a few numbers worth staring at. Below are our game-by-game predictions for every 2026 NFL Week 3 matchup, from the Thursday opener in Green Bay through the Monday night finale in Chicago. Every pick is set against the current spread, we flag the upsets we actually like, and there is a free printable pick sheet at the bottom so you can fill in the whole slate yourself.
Quick Facts
- Slate: Thursday, September 24 (Falcons at Packers), 14 games on Sunday, September 27, and Monday, September 28 (Eagles at Bears).
- Marquee games: Chargers at Bills, Chiefs at Dolphins, Ravens at Cowboys, and Eagles at Bears on Monday night.
- Our upset picks: Cowboys over Ravens and Broncos over Rams.
- Printable: a game-by-game pick sheet with spreads and totals is below.
Week 3 Predictions: Every Game
| Matchup | Spread | Our pick |
|---|---|---|
| Falcons at Packers | Packers -7.5 | Packers |
| Panthers at Browns | Panthers -1.5 | Panthers |
| Bengals at Steelers | Bengals -1.5 | Bengals |
| Texans at Colts | Texans -1.5 | Texans |
| Chiefs at Dolphins | Chiefs -7.5 | Chiefs |
| Chargers at Bills | Bills -3.5 | Bills |
| Patriots at Jaguars | Jaguars -1.5 | Jaguars |
| Jets at Lions | Lions -9.5 | Lions |
| Seahawks at Commanders | Seahawks -3.5 | Seahawks |
| Titans at Giants | Giants -3.5 | Giants |
| Cardinals at 49ers | 49ers -11.5 | 49ers |
| Vikings at Buccaneers | Buccaneers -1.5 | Buccaneers |
| Ravens at Cowboys | Ravens -2.5 | Cowboys (upset) |
| Raiders at Saints | Saints -3.5 | Saints |
| Rams at Broncos | Rams -3.5 | Broncos (upset) |
| Eagles at Bears | Bears -1.5 | Eagles (upset, Bears QBs out) |
Injury Watch: QB Changes That Move These Picks
Two quarterback situations shifted after this board was first set, and both nudge the value.
Eagles at Bears (Monday night): Chicago is thin at quarterback. Caleb Williams is week-to-week with a hamstring injury and backup Tyson Bagent is in the concussion protocol, which puts veteran Case Keenum in line to start. That is enough for us to come off the Bears at -1.5 and lean the Eagles.
Seahawks at Commanders: Jayden Daniels is out with an elbow injury, so Marcus Mariota draws the start for Washington. A backup under center only firms up our Seattle side at -3.5.
Titans at Giants: Rookie Jaxson Dart is out with a concussion, so Russell Wilson is back under center for New York. The Giants stay favored at -3.5, but a veteran-led offense is a different look than the one this number was built on.
Falcons at Packers (Thursday): Atlanta turns to left-hander Michael Penix Jr. at quarterback. Green Bay is still our side at -7.5 in the opener, but Penix gives the Falcons a higher ceiling than the market expected.
Upset Watch
Cowboys over Ravens. Baltimore is a 2.5-point road favorite, but this is the highest total on the board at 51.5 for a reason. Both offenses can score in bunches, and Dallas at home in a track-meet script is exactly the kind of live home dog we like. Give us the Cowboys to win it outright, not just cover.
Broncos over Rams. Los Angeles laying 3.5 on the road at altitude is a tough ask in late September. Denver has the pass rush to make a rhythm passer uncomfortable, and Mile High is a real edge in a one-score game. We will take the Broncos to spring the upset.
Best Bets and Leans
- Broncos +3.5. Our headline upset doubles as our favorite number on the card. The points plus the altitude is a strong combination.
- Under 39.5 in Panthers at Browns. This is the lowest total of the week. A grind-it-out game between two defense-first teams can stay under even in a tight finish.
- Cardinals +11.5. Double-digit road spreads in September division games tend to tighten late. We would rather have the points than lay them with San Francisco.
Picks and leans are for entertainment. Lines move, so check the current numbers before you do anything, and please play responsibly.
Storylines to Watch
San Francisco is the biggest favorite of the week, laying 11.5 at home against Arizona. Numbers that large shift the focus to backdoor covers and whether the starters stay on the field into the fourth quarter.
The Eagles close the week as road underdogs in Chicago, but that line was set before the Bears’ quarterback room thinned out (see the injury note above). With Caleb Williams and Tyson Bagent both banged up, a short-handed Chicago offense makes this Monday nighter a much better get-right spot for Philadelphia.
Three of the tightest lines on the board are road favorites, with the Panthers, Bengals and Texans all laying 1.5 away from home. Those coin-flip games are where pick pools get decided. Meanwhile Chargers at Bills and Chiefs at Dolphins hand the AFC picture its first real measuring sticks of the season.
Printable Week 3 Pick Sheet
Download the free printable pick sheet: every game from the Thursday opener to the Monday night finale, with the spread and over/under printed and blank columns for your pick and the final score. There is a tiebreaker line and a link back to this page in the footer.
More from Sports Brackets
- 2026 NFL Week 3 Pick’em with Odds: spreads, totals and a printable sheet
- 2026 NFL Week 3 TV Coverage Map: what is on in your market
- 2026 NFL Standings
- 2026 NFL Week 2 Predictions
Frequently Asked Questions
What are the best Week 3 upset picks?
We like the Cowboys to beat the Ravens outright at home in the highest-total game of the week, and the Broncos to knock off the Rams at altitude as home underdogs. Both are one-score projections rather than blowout calls.
Where do the spreads come from?
The spreads and totals here match our Week 3 pick’em with odds page and reflect consensus market numbers as of publication. Lines move during the week, so confirm the current number before you lock anything in.
Is there a printable pick sheet?
Yes. The free printable pick sheet above lists every game with the spread and over/under and leaves blank columns for your pick and the final score. It opens in a new tab and links back to this article.
